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Osteoporosis

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Bisphosphonates

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Now you can safely and effectively manage your osteoporosis with FosteumPLUS®

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What makes us Special?

Limbrel is a non-NSAID prescription made with natural ingredients that is safe and effective for the long-term management of osteoarthritis symptoms. Unlike traditional chronic OA pain medications that treat the symptoms (like NSAIDs), Limbrel works on underlying metabolic causes of joint discomfort.

Limbrel is a medical food, which is regulated by the FDA, but in a unique class separate from drugs and dietary supplements. Limbrel contains only ingredients that have been designated as GRAS (Generally Recognized As Safe) for wide populations, a strict safety standard set by the FDA.

Medical foods are intended for the dietary management of a disease, and must be used under a physician’s supervision. Medical foods are prescribed for people with ongoing chronic diseases. Limbrel is indicated for the dietary management of osteoarthritis, rebalancing metabolic processes that are specific to OA.

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References: 1. Burnett BP, Bitto A, Sqadrito F, Levy RM, Pillai L. 2011. Flavocoxid Inhibits Phospholipase A2, Peroxidase Moieties of the Cyclooxygenases (COX), 5-Lipoxygenase, Modifies COX-2 Gene Expression and Acts as an Antioxidant. Mediators Inflamm. 2011:385780, published online June 22, doi: 10.1155/2011/385780. 2. Levy R, Saikovsky R, Schmidt E, Khokhlov A, Burnett BP. 2009. Efficacy of flavocoxid compared with naproxen in subjects with osteoarthritis of the knee: a randomized, double-blind pilot study. Nutr Res. 29(5):298-304. 3. Levy R, Khokhlov A, Kopenkin S, Bart B, Ermolova T, Kantemirova R, Mazurov V, Bell M, Caldron P, Pillai L, Burnett BP. Efficacy and safety of flavocoxid, a novel therapeutic, compared with naproxen: a randomized multicenter controlled trial in subjects with osteoarthritis of the knee. Advances in Therapy. 2010; 27:731-42. 4. Levy RM, Khokhlov A, Kopenkin S, Bart B, Ermolova T, Kantemirova R, Mazurov V, Bell M, Caldron P. Pillai L, Burnett BP. 2010b. Efficacy and safety of flavocoxid compared with naproxen in subjects with osteoarthritis of the knee—a subset analysis. Adv Ther. 27(12):953-62. 5. Pillai L, Burnett BP, Levy RM for the GOAL Study Cooperative Group. Open-label, post-marketing study of flavocoxid, a novel dual pathway inhibitor anti-inflammatory agent of botanical origin: the GOAL study. Current Medical Research and Opinion. 2010; 26(5):1055-1063. 6. Data on file, post marketing surveillance report, June 2014. 7. Pillai L, Levy R, Yimam M, Zhao Y, Jia Q, Burnett BP. Flavoxocid, an anti-inflammatory agent of botanical origin, does not affect coagulation or interact with anticoagulation therapies. Advances in Therapy. 2010; 27(6):400-11